Everton produced a thrilling display to outclass a woeful Manchester United at Goodison Park and expose all the problems facing Red Devils manager Ole Gunnar Solskjaer.
United face a fight to secure a Premier League top-four place and Champions League football next season after 90 minutes which were little other than torture against a rampant Everton.
United goalkeeper David de Gea had saved superbly from Richarlison before the Brazilian hooked in an acrobatic 13th-minute volley to set the tone for a magnificent display from Marco Silva's side.
De Gea was beaten by Gylfi Sigurdsson's low 25-yard drive, going down late, as Everton took total control.
Everton did not let up after the break, Lucas Digne scoring from long range after De Gea punched out a corner, before substitute Theo Walcott ran clear on to Sigurdsson's pass to slide home the fourth.
United have lost six of their past eight games in all competitions, while a fifth successive away defeat - for the first time since 1981 - leaves them facing the prospect of Europa League football next season.
Everton in devastating form
Everton are on a hot streak at Goodison Park but this can rank alongside the finest displays seen at the famous old stadium in many seasons.
Yes, much will be made of United's obvious deficiencies, but it would be a gross injustice to ignore a magnificent performance from a side who have drawn with Liverpool and beaten Chelsea, Arsenal and United in their past four home games without conceding a goal.
Everton swarmed all over United from the first whistle and there was never a moment when they looked like relinquishing control.
Silva's pressing approach saw United harassed mercilessly for 90 minutes, but this was not simply about work-rate - Everton were full of skill, pace and athleticism.
Idrissa Gueye was the fulcrum in midfield while Sigurdsson and the gifted Brazilian Bernard were the creators-in-chief from first to last.
There may have been some doubts expressed about Silva's position not so long ago, but this blistering run of home form - and a style which will win full favour from Everton's fans - surely means he will be given time to build, as he should.